Sohini Ramachandran Explained
Sohini Ramachandran |
Alma Mater: | Stanford University |
Doctoral Advisor: | Marcus Feldman |
Education: | Stanford University |
Thesis Title: | The signature of historical migrations on human population genetic data |
Thesis Url: | https://www.worldcat.org/oclc/ |
Thesis Year: | 2007 |
Website: | https://brown.edu/Research/Ramachandran_Lab/ |
Sohini Ramachandran is professor at Brown University known for her work in evolutionary biology and population genetics.
Early life and education
Ramachandran's parents were both professors.[1] In the summer before her senior year of high school, Ramachandran completed a research project in plant genomics under the guidance of Marcus Feldman, which won her the fourth place prize in the 1998 Westinghouse Science Talent Search,[2] where when she was the youngest finalist in the group.[3] Ramachandran earned a B.S. from Stanford University in 2002. She went on to complete a Ph.D. at Stanford University in the Department of Biological Sciences, advised by Marcus Feldman. Her dissertation research was dissertation was titled "The signature of historical migrations on human population genetic data."[4] Following her PhD, she was in the Harvard Society of Fellows as a postdoctoral researcher with John Wakeley in Harvard University's Department of Organismic and Evolutionary Biology.[5] She moved to Brown University in 2010 and was promoted to professor in 2021. In 2019, she was a fellow at the Swedish Collegium for Advanced Study.[6]
Research
Ramachandran's research group uses statistical and mathematical modeling techniques to study evolutionary biology and population genetics. Her early research examined the genetic relationships originating within people from Africa,[7] [8] where she showed that diversity decreases as distance from Africa increases.[9] She has also investigated the use of genetic tools to track infectious diseases[10] [11] and shown that while more outbreaks are occurring, fewer people are getting infected.[12] She has also shown a lack of genetic evidence for selection for language at the FOXP2 site.[13]
Selected publications
- Li . Jun Z. . Absher . Devin M. . Tang . Hua . Southwick . Audrey M. . Casto . Amanda M. . Ramachandran . Sohini . Cann . Howard M. . Barsh . Gregory S. . Feldman . Marcus . Cavalli-Sforza . Luigi L. . Myers . Richard M. . 2008-02-22 . Worldwide Human Relationships Inferred from Genome-Wide Patterns of Variation . Science . en . 319 . 5866 . 1100–1104 . 10.1126/science.1153717 . 18292342 . 2008Sci...319.1100L . 53541133 . 0036-8075.
- Ramachandran . Sohini . Deshpande . Omkar . Roseman . Charles C. . Rosenberg . Noah A. . Feldman . Marcus W. . Cavalli-Sforza . L. Luca . 2005 . Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa . Proceedings of the National Academy of Sciences . en . 102 . 44 . 15942–15947 . 10.1073/pnas.0507611102 . 0027-8424 . 1276087 . 16243969. 2005PNAS..10215942R . free .
- Wang . Sijia . Lewis . Cecil M. Jr. . Jakobsson . Mattias . Ramachandran . Sohini . Ray . Nicolas . Bedoya . Gabriel . Rojas . Winston . Parra . Maria V. . Molina . Julio A. . Gallo . Carla . Mazzotti . Guido . 2007-11-23 . Genetic Variation and Population Structure in Native Americans . PLOS Genetics . en . 3 . 11 . e185 . 10.1371/journal.pgen.0030185 . 1553-7404 . 2082466 . 18039031 . free .
- Ramachandran . Sohini . Rosenberg . Noah A. . Zhivotovsky . Lev A. . Feldman . Marcus W. . 2004 . Robustness of the inference of human population structure: A comparison of X-chromosomal and autosomal microsatellites . Human Genomics . en . 1 . 2 . 87–97 . 10.1186/1479-7364-1-2-87 . 1479-7364 . 3525066 . 15601537 . free .
Honors and awards
In 2012, Ramachandran received a Sloan Research Fellowship[14] and was named a Pew Scholar.[15] From Brown University she has received the Henry Merritt Wriston Fellowship (2016)[16] and the Philip J. Bray Award for excellence in teaching.[17] In 2019, she received a Presidential Early Career Award in Science and Engineering.[18] [19]
External links
Notes and References
- Chen . Ling-Ling . Claw . Katrina G. . Ramachandran . Sohini . 2016 . A two-fold challenge: the experience of women of color in genomics . Genome Biology . en . 17 . 1 . 210 . 10.1186/s13059-016-1075-0 . 1474-760X . 5059990 . 27729075 . free .
- News: Chiu . Yvonne . 1998-03-09 . Fair Oaks teen gets national honor . 2 . The Sacramento Bee . 2022-04-17.
- News: Alcala . Carlos . 1998-01-28 . Fair Oaks teen, like sister, is on academic fast track . https://www.newspapers.com/clip/99945142/fair-oaks-teen-like-sister-is-on/,https://www.newspapers.com/clip/99945183/ . The Sacramento Bee . 2022-04-17.
- The signature of historical migrations on human population genetic data . 2007 . English . Sohini . Ramachandran. 269371999.
- Web site: Sohini Ramachandran Lab: people . 2022-04-17 . brown.edu.
- Web site: SCAS: Sohini Ramachandran . 2022-01-22 . www.swedishcollegium.se.
- Ramachandran . Sohini . Deshpande . Omkar . Roseman . Charles C. . Rosenberg . Noah A. . Feldman . Marcus W. . Cavalli-Sforza . L. Luca . 2005 . Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa . Proceedings of the National Academy of Sciences . en . 102 . 44 . 15942–15947 . 10.1073/pnas.0507611102 . 0027-8424 . 1276087 . 16243969. 2005PNAS..10215942R . free .
- Henn . Brenna M. . Gignoux . Christopher R. . Jobin . Matthew . Granka . Julie M. . Macpherson . J. M. . Kidd . Jeffrey M. . Rodríguez-Botigué . Laura . Ramachandran . Sohini . Hon . Lawrence . Brisbin . Abra . Lin . Alice A. . 2011-03-29 . Hunter-gatherer genomic diversity suggests a southern African origin for modern humans . Proceedings of the National Academy of Sciences . en . 108 . 13 . 5154–5162 . 10.1073/pnas.1017511108 . 0027-8424 . 3069156 . 21383195. free .
- Web site: Scudellari . Megan . June 2012 . Sohini Ramachandran: Population Tracker . 2022-04-17 . The Scientist Magazine® . en.
- Smith . Katherine F. . Goldberg . Michael . Rosenthal . Samantha . Carlson . Lynn . Chen . Jane . Chen . Cici . Ramachandran . Sohini . 2014-12-06 . Global rise in human infectious disease outbreaks . Journal of the Royal Society Interface . 11 . 101 . 20140950 . 10.1098/rsif.2014.0950 . 4223919 . 25401184.
- Nakka . Priyanka . Raphael . Benjamin J . Ramachandran . Sohini . 2016-10-01 . Gene and Network Analysis of Common Variants Reveals Novel Associations in Multiple Complex Diseases . Genetics . en . 204 . 2 . 783–798 . 10.1534/genetics.116.188391 . 1943-2631 . 5068862 . 27489002.
- News: Berman . Jessica . October 29, 2014 . Global Infection Outbreaks Rise over Past 30 Years . Voice of America News / FIND; Washington.
- Atkinson . Elizabeth Grace . Audesse . Amanda Jane . Palacios . Julia Adela . Bobo . Dean Michael . Webb . Ashley Elizabeth . Ramachandran . Sohini . Henn . Brenna Mariah . 2018-09-06 . No Evidence for Recent Selection at FOXP2 among Diverse Human Populations . Cell . English . 174 . 6 . 1424–1435.e15 . 10.1016/j.cell.2018.06.048 . 0092-8674 . 6128738 . 30078708.
- Web site: August 23, 2012 . Sohini Ramachandran, Ph.D. . 2022-01-13 . pew.org . en.
- News: July 3, 2012 . Eight Women Win Pew Scholarships in the Biomedical Sciences . Women in Academia Report; Bartonsville.
- Web site: Sohini Ramchandran awarded Wriston Fellowship . 2022-04-17 . CCMB Brown University . en.
- Web site: Gimenes . Livia . 2021-07-03 . Sohini Ramachandran Receives The Philip J. Bray Award For Excellence In Teaching In The Physical Sciences . 2022-04-17 . awards.cs.brown.edu . en.
- Web site: Two Brown researchers earn top White House award for early-career scientists. 2022-01-13. Brown University. en.
- Web site: Abbey Bigler and Talylor Walter . PECASE Honoree Sohini Ramachandran Studies the Genetic Foundations of Traits in Diverse Populations . 2022-04-17 . NIGMS Biomedical Beat Blog . 26 February 2020 . en-US.