Sodium-coupled neutral amino acid transporter 3 explained

Sodium-coupled neutral amino acid transporter 3 is a protein that in humans is encoded by the SLC38A3 gene.^{[1] [2] [3]}

See also

• Solute carrier family

Further reading

• Hartley JL, Temple GF, Brasch MA . DNA cloning using in vitro site-specific recombination. . Genome Res. . 10 . 11 . 1788–95 . 2001 . 11076863 . 10.1101/gr.143000 . 310948 .
• Lerman MI, Minna JD . The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium. . Cancer Res. . 60 . 21 . 6116–33 . 2000 . 11085536 .
• Wiemann S, Weil B, Wellenreuther R, etal . Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. . Genome Res. . 11 . 3 . 422–35 . 2001 . 11230166 . 10.1101/gr.GR1547R . 311072 .
• Simpson JC, Wellenreuther R, Poustka A, etal . Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. . EMBO Rep. . 1 . 3 . 287–92 . 2001 . 11256614 . 10.1093/embo-reports/kvd058 . 1083732 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Boehmer C, Okur F, Setiawan I, etal . Properties and regulation of glutamine transporter SN1 by protein kinases SGK and PKB. . Biochem. Biophys. Res. Commun. . 306 . 1 . 156–62 . 2003 . 12788082 . 10.1016/S0006-291X(03)00921-5 .
• Sidoryk M, Matyja E, Dybel A, etal . Increased expression of a glutamine transporter SNAT3 is a marker of malignant gliomas. . NeuroReport . 15 . 4 . 575–8 . 2004 . 15094455 . 10.1097/00001756-200403220-00001 . 24489896 .
• Suzuki Y, Yamashita R, Shirota M, etal . Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. . Genome Res. . 14 . 9 . 1711–8 . 2004 . 15342556 . 10.1101/gr.2435604 . 515316 .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Wiemann S, Arlt D, Huber W, etal . From ORFeome to biology: a functional genomics pipeline. . Genome Res. . 14 . 10B . 2136–44 . 2004 . 15489336 . 10.1101/gr.2576704 . 528930 .
• Mehrle A, Rosenfelder H, Schupp I, etal . The LIFEdb database in 2006. . Nucleic Acids Res. . 34 . Database issue . D415–8 . 2006 . 16381901 . 10.1093/nar/gkj139 . 1347501 .
• Kholodnyuk ID, Kozireva S, Kost-Alimova M, etal . Down regulation of 3p genes, LTF, SLC38A3 and DRR1, upon growth of human chromosome 3-mouse fibrosarcoma hybrids in severe combined immunodeficiency mice. . Int. J. Cancer . 119 . 1 . 99–107 . 2006 . 16432833 . 10.1002/ijc.21794 . 27171340 . free .
• Muzny DM, Scherer SE, Kaul R, etal . The DNA sequence, annotation and analysis of human chromosome 3. . Nature . 440 . 7088 . 1194–8 . 2006 . 16641997 . 10.1038/nature04728 . 2006Natur.440.1194M . free .

Notes and References

1. Chaudhry FA, Reimer RJ, Krizaj D, Barber D, Storm-Mathisen J, Copenhagen DR, Edwards RH . Jon Storm-Mathisen . Molecular analysis of system N suggests novel physiological roles in nitrogen metabolism and synaptic transmission . Cell . 99 . 7 . 769–80 . Feb 2000 . 10619430 . 10.1016/S0092-8674(00)81674-8 . 17639583 . free .
2. Fei YJ, Sugawara M, Nakanishi T, Huang W, Wang H, Prasad PD, Leibach FH, Ganapathy V . Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+- and H+-coupled glutamine transporter . J Biol Chem . 275 . 31 . 23707–17 . Sep 2000 . 10823827 . 10.1074/jbc.M002282200 . free .
3. Web site: Entrez Gene: SLC38A3 solute carrier family 38, member 3.