Sodium/hydrogen exchanger 5 explained

Sodium/hydrogen exchanger 5 is a protein that in humans is encoded by the SLC9A5 gene.^{[1] [2] [3]}

See also

• Solute carrier family

Further reading

• Baird NR, Orlowski J, Szabó EZ, etal . Molecular cloning, genomic organization, and functional expression of Na+/H+ exchanger isoform 5 (NHE5) from human brain. . J. Biol. Chem. . 274 . 7 . 4377–82 . 1999 . 9933641 . 10.1074/jbc.274.7.4377 . free .
• Szaszi K, Paulsen A, Szabo EZ, etal . Clathrin-mediated endocytosis and recycling of the neuron-specific Na+/H+ exchanger NHE5 isoform. Regulation by phosphatidylinositol 3'-kinase and the actin cytoskeleton. . J. Biol. Chem. . 277 . 45 . 42623–32 . 2003 . 12205089 . 10.1074/jbc.M206629200 . free .
• Chagnon P, Michaud J, Mitchell G, etal . A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis. . Am. J. Hum. Genet. . 71 . 6 . 1443–9 . 2003 . 12417987 . 10.1086/344580 . 378590 .
• Inoue H, Nakamura Y, Nagita M, etal . Calcineurin homologous protein isoform 2 (CHP2), Na+/H+ exchangers-binding protein, is expressed in intestinal epithelium. . Biol. Pharm. Bull. . 26 . 2 . 148–55 . 2003 . 12576672 . 10.1248/bpb.26.148 . free .
• Lin WM, Chen XH, Xu R, etal . [Tissue-specific expression of Na(+)-H(+) exchanger isoforms at two developmental stages of human fetus] . Sheng li xue bao: [Acta Physiologica Sinica] . 55 . 1 . 79–82 . 2003. 12598940 .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Szabó EZ, Numata M, Lukashova V, etal . beta-Arrestins bind and decrease cell-surface abundance of the Na+/H+ exchanger NHE5 isoform. . Proc. Natl. Acad. Sci. U.S.A. . 102 . 8 . 2790–5 . 2005 . 15699339 . 10.1073/pnas.0407444102 . 549460 . 2005PNAS..102.2790S . free .
• Onishi I, Lin PJ, Diering GH, etal . RACK1 associates with NHE5 in focal adhesions and positively regulates the transporter activity. . Cell. Signal. . 19 . 1 . 194–203 . 2007 . 16920332 . 10.1016/j.cellsig.2006.06.011 .

Notes and References

1. Klanke CA, Su YR, Callen DF, Wang Z, Meneton P, Baird N, Kandasamy RA, Orlowski J, Otterud BE, Leppert M, etal . Molecular cloning and physical and genetic mapping of a novel human Na+/H+ exchanger (NHE5/SLC9A5) to chromosome 16q22.1 . Genomics . 25 . 3 . 615–22 . Jun 1995 . 7759094 . 10.1016/0888-7543(95)80002-4 .
2. Attaphitaya S, Park K, Melvin JE . Molecular cloning and functional expression of a rat Na+/H+ exchanger (NHE5) highly expressed in brain . J Biol Chem . 274 . 7 . 4383–8 . Mar 1999 . 9933642 . 10.1074/jbc.274.7.4383 . free .
3. Web site: Entrez Gene: SLC9A5 solute carrier family 9 (sodium/hydrogen exchanger), member 5.