Sodalis glossinidius explained

Sodalis glossinidius is a species of bacteria, the type and only species of its genus. It is a microaerophilic secondary endosymbiont of the tsetse fly. Strain M1T is the type strain.^[1] Sodalis glossinidius is the only gammaproteobacterial insect symbiont to be cultured and thus amenable to genetic modification, suggesting that it could be used as part of a control strategy by vectoring antitrypanosome genes. The organism may increase the susceptibility of tsetse flies to trypanosomes.^[2]

Despite gene erosion and pseudogene multiplication in a genome of Sodalis glossinidius,^[3] these pseudogenes remain actively transcribed.^[4]

Parasites

S. glossinidius is itself host to a prophage discovered by Clark et al. 2007.^[5]

Further reading

• Dale C, Young SA, Haydon DT, Welburn SC . The insect endosymbiont Sodalis glossinidius utilizes a type III secretion system for cell invasion . . 98 . 4 . 1883–8 . February 2001 . 11172045 . 29351 . 10.1073/pnas.98.4.1883 . free .
• Akman L, Rio RV, Beard CB, Aksoy S . Genome size determination and coding capacity of Sodalis glossinidius, an enteric symbiont of tsetse flies, as revealed by hybridization to Escherichia coli gene arrays . . 183 . 15 . 4517–25 . August 2001 . 11443086 . 95346 . 10.1128/JB.183.15.4517-4525.2001 .
• Matthew CZ, Darby AC, Young SA, Hume LH, Welburn SC . The rapid isolation and growth dynamics of the tsetse symbiont Sodalis glossinidius . . 248 . 1 . 69–74 . July 2005 . 15961259 . 10.1016/j.femsle.2005.05.024 . free .

External links

• LPSN
  • Type strain of Sodalis glossinidius at BacDive - the Bacterial Diversity Metadatabase

Notes and References

1. Dale C, Maudlin I . Sodalis gen. nov. and Sodalis glossinidius sp. nov., a microaerophilic secondary endosymbiont of the tsetse fly Glossina morsitans morsitans . International Journal of Systematic Bacteriology . 49 Pt 1 . 1 . 267–75 . January 1999 . 10028272 . 10.1099/00207713-49-1-267 . free .
2. Darby AC, Lagnel J, Matthew CZ, Bourtzis K, Maudlin I, Welburn SC . Extrachromosomal DNA of the symbiont Sodalis glossinidius . . 187 . 14 . 5003–7 . July 2005 . 15995217 . 1169519 . 10.1128/JB.187.14.5003-5007.2005 .
3. Toh H, Weiss BL, Perkin SA, Yamashita A, Oshima K, Hattori M, Aksoy S . Massive genome erosion and functional adaptations provide insights into the symbiotic lifestyle of Sodalis glossinidius in the tsetse host . Genome Research . 16 . 2 . 149–56 . February 2006 . 16365377 . 1361709 . 10.1101/gr.4106106 .
4. Goodhead I, Blow F, Brownridge P, Hughes M, Kenny J, Krishna R, McLean L, Pongchaikul P, Beynon R, Darby AC . 6 . Large-scale and significant expression from pseudogenes in Sodalis glossinidius - a facultative bacterial endosymbiont . Microbial Genomics . 6 . 1 . January 2020 . 31922467 . 7067036 . 10.1099/mgen.0.000285 . free .
5. Kirsch . Joshua M. . Brzozowski . Robert S. . Faith . Dominick . Round . June L. . Secor . Patrick R. . Duerkop . Breck A. . Bacteriophage-Bacteria Interactions in the Gut: From Invertebrates to Mammals . . . 8 . 1 . 2021-09-29 . 2327-056X . 34255542 . 10.1146/annurev-virology-091919-101238 . 8484061 . 95–113.