| Official Name: | Smythe, Indiana |
| Settlement Type: | Unincorporated community |
| Pushpin Map: | Indiana#USA |
| Pushpin Label: | Smythe |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Indiana |
| Subdivision Type2: | County |
| Subdivision Name2: | Vanderburgh |
| Subdivision Type3: | Township |
| Subdivision Name3: | Knight |
| Timezone: | Central (CST) |
| Utc Offset: | -6 |
| Timezone Dst: | CDT |
| Utc Offset Dst: | -5 |
| Coordinates: | 37.9914°N -87.4925°W |
| Elevation Ft: | 387 |
| Postal Code Type: | ZIP code |
| Postal Code: | 47715 |
| Area Code: | 812, 930 |
| Blank1 Name: | FIPS code |
| Blank Name: | GNIS feature ID |
| Blank Info: | 443719 |
Smythe is an unincorporated community in Knight Township, Vanderburgh County, in the U.S. state of Indiana.
It is located within the city limits of Evansville.
Smythe was named after a local family of settlers.[1] An old variant name of the community was called Burkhart Station.[2]