Small nucleolar RNA SNORD77 explained

Small nucleolar RNA SNORD77
Symbol:SNORD77
Altsymbols:snoU77
Rfam:RF00591
Rna Type:Gene
snRNA; snoRNA; C/D-box
Tax Domain:Eukaryota

In molecular biology, SNORD77 (also known as U77) belongs to the C/D family of snoRNAs. It is predicted to guide 2'O-ribose methylation of large 28S rRNA subunit at position A1521.[1] The C/D snoRNAs U44, U47, U74, U75, U76, U78, U79, U80 and U81 share the same host gene as U77 (non-coding).[2]

Notes and References

  1. Tycowski KT, Aab A, Steitz JA . Guide RNAs with 5' caps and novel box C/D snoRNA-like domains for modification of snRNAs in metazoa . Current Biology . 14 . 22 . 1985–95 . November 2004 . 15556860 . 10.1016/j.cub.2004.11.003 . free .
  2. Lestrade L, Weber MJ . snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs . Nucleic Acids Research . 34 . Database issue . D158-62 . January 2006 . 16381836 . 1347365 . 10.1093/nar/gkj002 . 10.1.1.105.7552 .