Small nucleolar RNA SNORD21 explained
| Small nucleolar RNA SNORD21 |
| Symbol: | SNORD21 |
| Altsymbols: | U21 |
| Rfam: | RF00068 |
| Rna Type: | Gene
- snRNA; snoRNA; CD-box
|
| Tax Domain: | Eukaryota |
In molecular biology, U21 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. U21 is encoded within an intron of the gene for ribosomal protein L5 in mammals,[1] but within introns of the ADP ribosylation factor gene in Drosophila.[2] U21 snoRNA has a 13 nucleotide region of complementarity with an invariant region of eukaryotic 28S ribosomal RNA.
Notes and References
- Qu LH, Nicoloso M, Michot B, Azum MC, Caizergues-Ferrer M, Renalier MH, Bachellerie JP . U21, a novel small nucleolar RNA with a 13 nt. complementarity to 28S rRNA, is encoded in an intron of ribosomal protein L5 gene in chicken and mammals . Nucleic Acids Research . 22 . 20 . 4073–81 . October 1994 . 7937132 . 331892 . 10.1093/nar/22.20.4073 .
- Renalier MH, Nicoloso M, Qu LH, Bachellerie JP . SnoRNA U21 is also intron-encoded in Drosophila melanogaster but in a different host-gene as compared to warm-blooded vertebrates . FEBS Letters . 379 . 3 . 212–6 . February 1996 . 8603691 . 10.1016/0014-5793(95)01511-6 . 28632486 .
