Small nuclear ribonucleoprotein polypeptide F explained

Small nuclear ribonucleoprotein F is a protein that in humans is encoded by the SNRPF gene.^{[1] [2]}

Interactions

Small nuclear ribonucleoprotein polypeptide F has been shown to interact with DDX20,^[3] Small nuclear ribonucleoprotein D2^[4] and Small nuclear ribonucleoprotein polypeptide E.^[4]

Further reading

• Sauterer RA, Goyal A, Zieve GW . Cytoplasmic assembly of small nuclear ribonucleoprotein particles from 6 S and 20 S RNA-free intermediates in L929 mouse fibroblasts . The Journal of Biological Chemistry . 265 . 2 . 1048–58 . January 1990 . 10.1016/S0021-9258(19)40157-9 . 1688550 . free .
• Feeney RJ, Sauterer RA, Feeney JL, Zieve GW . Cytoplasmic assembly and nuclear accumulation of mature small nuclear ribonucleoprotein particles . The Journal of Biological Chemistry . 264 . 10 . 5776–83 . April 1989 . 10.1016/S0021-9258(18)83617-1 . 2522439 . free .
• Woppmann A, Rinke J, Lührmann R . Direct cross-linking of snRNP proteins F and 70K to snRNAs by ultra-violet radiation in situ . Nucleic Acids Research . 16 . 23 . 10985–1004 . December 1988 . 2974540 . 338992 . 10.1093/nar/16.23.10985 .
• Bonaldo MF, Lennon G, Soares MB . Normalization and subtraction: two approaches to facilitate gene discovery . Genome Research . 6 . 9 . 791–806 . September 1996 . 8889548 . 10.1101/gr.6.9.791 . free .
• Plessel G, Lührmann R, Kastner B . Electron microscopy of assembly intermediates of the snRNP core: morphological similarities between the RNA-free (E.F.G) protein heteromer and the intact snRNP core . Journal of Molecular Biology . 265 . 2 . 87–94 . January 1997 . 9020971 . 10.1006/jmbi.1996.0713 .
• Fury MG, Zhang W, Christodoulopoulos I, Zieve GW . Multiple protein: protein interactions between the snRNP common core proteins . Experimental Cell Research . 237 . 1 . 63–9 . November 1997 . 9417867 . 10.1006/excr.1997.3750 .
• Kambach C, Walke S, Young R, Avis JM, de la Fortelle E, Raker VA, Lührmann R, Li J, Nagai K . Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs . Cell . 96 . 3 . 375–87 . February 1999 . 10025403 . 10.1016/S0092-8674(00)80550-4 . 17379935 . free .
• Bühler D, Raker V, Lührmann R, Fischer U . Essential role for the tudor domain of SMN in spliceosomal U snRNP assembly: implications for spinal muscular atrophy . Human Molecular Genetics . 8 . 13 . 2351–7 . December 1999 . 10556282 . 10.1093/hmg/8.13.2351 . free .
• Charroux B, Pellizzoni L, Perkinson RA, Shevchenko A, Mann M, Dreyfuss G . Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems . The Journal of Cell Biology . 147 . 6 . 1181–94 . December 1999 . 10601333 . 2168095 . 10.1083/jcb.147.6.1181 .
• Charroux B, Pellizzoni L, Perkinson RA, Yong J, Shevchenko A, Mann M, Dreyfuss G . Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli . The Journal of Cell Biology . 148 . 6 . 1177–86 . March 2000 . 10725331 . 2174312 . 10.1083/jcb.148.6.1177 .
• Urlaub H, Raker VA, Kostka S, Lührmann R . Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure . The EMBO Journal . 20 . 1–2 . 187–96 . January 2001 . 11226169 . 140196 . 10.1093/emboj/20.1.187 .
• Pellizzoni L, Baccon J, Rappsilber J, Mann M, Dreyfuss G . Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component . The Journal of Biological Chemistry . 277 . 9 . 7540–5 . March 2002 . 11748230 . 10.1074/jbc.M110141200 . free .
• Friesen WJ, Wyce A, Paushkin S, Abel L, Rappsilber J, Mann M, Dreyfuss G . A novel WD repeat protein component of the methylosome binds Sm proteins . The Journal of Biological Chemistry . 277 . 10 . 8243–7 . March 2002 . 11756452 . 10.1074/jbc.M109984200 . free .
• Jurica MS, Licklider LJ, Gygi SR, Grigorieff N, Moore MJ . Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis . RNA . 8 . 4 . 426–39 . April 2002 . 11991638 . 1370266 . 10.1017/S1355838202021088 .
• Will CL, Schneider C, Hossbach M, Urlaub H, Rauhut R, Elbashir S, Tuschl T, Lührmann R . The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome . RNA . 10 . 6 . 929–41 . June 2004 . 15146077 . 1370585 . 10.1261/rna.7320604 .
• Lehner B, Sanderson CM . A protein interaction framework for human mRNA degradation . Genome Research . 14 . 7 . 1315–23 . July 2004 . 15231747 . 442147 . 10.1101/gr.2122004 .
• Ma Y, Dostie J, Dreyfuss G, Van Duyne GD . The Gemin6-Gemin7 heterodimer from the survival of motor neurons complex has an Sm protein-like structure . Structure . 13 . 6 . 883–92 . June 2005 . 15939020 . 10.1016/j.str.2005.03.014 . free .

Notes and References

1. Hermann H, Fabrizio P, Raker VA, Foulaki K, Hornig H, Brahms H, Lührmann R . snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactions . The EMBO Journal . 14 . 9 . 2076–88 . May 1995 . 7744013 . 398308 . 10.1002/j.1460-2075.1995.tb07199.x.
2. Web site: Entrez Gene: SNRPF small nuclear ribonucleoprotein polypeptide F.
3. Charroux B, Pellizzoni L, Perkinson RA, Shevchenko A, Mann M, Dreyfuss G . Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems . The Journal of Cell Biology . 147 . 6 . 1181–94 . December 1999 . 10601333 . 2168095 . 10.1083/jcb.147.6.1181 .
4. Fury MG, Zhang W, Christodoulopoulos I, Zieve GW . Multiple protein: protein interactions between the snRNP common core proteins . Experimental Cell Research . 237 . 1 . 63–9 . November 1997 . 9417867 . 10.1006/excr.1997.3750 .