Small nuclear ribonucleoprotein polypeptide C explained

U1 small nuclear ribonucleoprotein C is a protein that in humans is encoded by the SNRPC gene.^{[1] [2] [3]}

Interactions

Small nuclear ribonucleoprotein polypeptide C has been shown to interact with Ewing sarcoma breakpoint region 1.^[4]

Further reading

• Yamamoto K, Miura H, Moroi Y, Yoshinoya S, Goto M, Nishioka K, Miyamoto T . Isolation and characterization of a complementary DNA expressing human U1 small nuclear ribonucleoprotein C polypeptide . Journal of Immunology . 140 . 1 . 311–7 . January 1988 . 10.4049/jimmunol.140.1.311 . 2961811 . 45846091 . free .
• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides . Gene . 138 . 1–2 . 171–4 . January 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Nelissen RL, Gunnewiek JM, Lambermon MH, Van Venrooij WJ . Cloning and characterization of two processed pseudogenes and the cDNA for the murine U1 snRNP-specific protein C . Gene . 184 . 2 . 273–8 . January 1997 . 9031639 . 10.1016/S0378-1119(96)00612-9 . 2066/27882 . free .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library . Gene . 200 . 1–2 . 149–56 . October 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 .
• Dumortier H, Klein Gunnewiek J, Roussel JP, van Aarssen Y, Briand JP, van Venrooij WJ, Muller S . At least three linear regions but not the zinc-finger domain of U1C protein are exposed at the surface of the protein in solution and on the human spliceosomal U1 snRNP particle . Nucleic Acids Research . 26 . 23 . 5486–91 . December 1998 . 9826776 . 147990 . 10.1093/nar/26.23.5486 .
• Charroux B, Pellizzoni L, Perkinson RA, Yong J, Shevchenko A, Mann M, Dreyfuss G . Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli . The Journal of Cell Biology . 148 . 6 . 1177–86 . March 2000 . 10725331 . 2174312 . 10.1083/jcb.148.6.1177 .
• Knoop LL, Baker SJ . The splicing factor U1C represses EWS/FLI-mediated transactivation . The Journal of Biological Chemistry . 275 . 32 . 24865–71 . August 2000 . 10827180 . 10.1074/jbc.M001661200 . free .
• Pellizzoni L, Baccon J, Rappsilber J, Mann M, Dreyfuss G . Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component . The Journal of Biological Chemistry . 277 . 9 . 7540–5 . March 2002 . 11748230 . 10.1074/jbc.M110141200 . free .
• Förch P, Puig O, Martínez C, Séraphin B, Valcárcel J . The splicing regulator TIA-1 interacts with U1-C to promote U1 snRNP recruitment to 5' splice sites . The EMBO Journal . 21 . 24 . 6882–92 . December 2002 . 12486009 . 139089 . 10.1093/emboj/cdf668 .
• Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, Zhang H, Zha XM, Polakiewicz RD, Comb MJ . Immunoaffinity profiling of tyrosine phosphorylation in cancer cells . Nature Biotechnology . 23 . 1 . 94–101 . January 2005 . 15592455 . 10.1038/nbt1046 . 7200157 .
• Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M . Nucleolar proteome dynamics . Nature . 433 . 7021 . 77–83 . January 2005 . 15635413 . 10.1038/nature03207 . 2005Natur.433...77A . 4344740 .

Notes and References

1. Sillekens PT, Beijer RP, Habets WJ, van Venrooij WJ . Human U1 snRNP-specific C protein: complete cDNA and protein sequence and identification of a multigene family in mammals . Nucleic Acids Research . 16 . 17 . 8307–21 . September 1988 . 2971157 . 338560 . 10.1093/nar/16.17.8307 .
2. Gunnewiek JM, van Aarssen Y, Wassenaar R, Legrain P, van Venrooij WJ, Nelissen RL . Homodimerization of the human U1 snRNP-specific protein C . Nucleic Acids Research . 23 . 23 . 4864–71 . December 1995 . 8532530 . 307476 . 10.1093/nar/23.23.4864 .
3. Web site: Entrez Gene: SNRPC small nuclear ribonucleoprotein polypeptide C.
4. Knoop LL, Baker SJ . The splicing factor U1C represses EWS/FLI-mediated transactivation . The Journal of Biological Chemistry . 275 . 32 . 24865–71 . August 2000 . 10827180 . 10.1074/jbc.M001661200 . free .