| Skyline High School | |
| Motto: | Creating a legacy of excellence |
| Established: | 1999 |
| Type: | Public secondary (U.S.) |
| Us Nces School Id: | 040497001830 |
| Principal: | Gregory Mendez |
| Address: | 845 S. Crismon Rd. |
| Zipcode: | 85208 |
| Country: | US |
| Us Nces District Id: | 0404970 |
| Enrollment: | 2,389 (2020-2021)[1] |
| Ratio: | 19.34 |
| Teaching Staff: | 123.50 (FTE) |
| Mascot: | Coyote |
| Yearbook: | Skybound |
| Homepage: | mpsaz.org/skyline |
| Picture Caption: | Skyline High School |
Skyline High School is a public high school in the eastern part of Mesa, Arizona. Skyline is the youngest of the six high schools located in the Mesa Unified School District. Skyline opened in 1999 and houses students in grades 9–12. Skyline High School is a four-year, public, comprehensive high school with an estimated enrollment of 2,400 students. The school is accredited by the North Central Association.
During the 2020-2021 school year, the demographic break of the 2,389 students enrolled was:
| 2004 | Michael Wirth | 4–20 (0–13) | No Appearance | |
| 2005 | Mike Parillo | 4–21 (0–3) | NA | |
| 2006 | M. Wirth | 6–21 (2–8) | at Red Mountain (L) 76–64 | |
| 2007 | M. Wirth | 12–26 (1–7) | at Horizon (L) 73–49 | |
| 2008 | M. Wirth | 17–12 (3–5) | NA | |
| 2009 | M. Wirth | 14–14 (4–8) | NA | |
| 2010 | M. Wirth | 11–14 (3–9) | NA | |
| 2011 | M. Wirth | 7–18 (0–14) | NA | |
| 2012 | M. Wirth | 7–17 (0–13) | NA | |
| 2013 | Matthew Johnson | 8–17 (1–11) | NA | |
| 2014 | M. Johnson | 12–14 (3–9) | NA | |
| 2015 | James Capriotti | 3–22 (1–7) | NA | |
| 2016 | J. Capriotti | 12–14 (2–8) | NA | |
| 2017 | J. Capriotti | 14–13 (4–6) | NA | |
| 2018 | J. Capriotti | 19–8 (7–3) | at Perry (L) 74–71 (OT) | |
| 2019 | J. Capriotti | 27–3 (10–0) | vs. Corona del Sol (W) 81–53vs. Perry (W) 43–41 at Desert Vista (L) 63–44 | |
| 2020 | Mitch Armour | 4–13 (3–7) | N/A | |
| 2021 | M. Armour | 1-22 (1-10) | N/A | |
| 2022 | Cory Hoff | 6-20 (1-9) | N/A | |
| 2023 | Angel Ung | 2-5 (0-0) | N/A |
| 2004 | Pete Jonovich | 3–7 (0–6) | No Appearance | |
| 2005 | P. Jonovich | 3–7 (0–5) | NA | |
| 2006 | P. Jonovich | 2–10 (1–4) | NA | |
| 2007 | P. Jonovich | 7-4 (2–2) | vs. Westview (L) 35–23 | |
| 2008 | P. Jonovich | 8–4–1 (2–2) | vs. La Joya Community (L) 50–28vs. Marcos de Niza (L) 38–3 | |
| 2009 | P. Jonovich | 2–9 (0–6) | NA | |
| 2010 | P. Jonovich | 1–10 (1–5) | NA | |
| 2011 | P. Jonovich | 3–7 (0–4) | NA | |
| 2012 | Angelo Paffumi | 5–5 (2–3) | NA | |
| 2013 | A. Paffumi | 6–5 (1–4) | vs. Chandler (L) 55–16 | |
| 2014 | A. Paffumi | 11–2 (5–1) | vs. Boulder Creek (W) 28–12vs. Hamilton (L) 21–14 | |
| 2015 | A. Paffumi | 12–1 (5–0) | vs. Sahuaro (W) 15–10vs. Mesa (W) 30–7 vs. Marcos de Niza (L) 44–37 | |
| 2016 | A. Paffumi | 9–2 (5–0) | vs. Red Mountain (L) 16–13 | |
| 2017 | A. Paffumi | 6–5 (4–1) | vs. Hamilton (L) 49–27 | |
| 2018 | A. Paffumi | 5–5 (4–1) | N/A | |
| 2019 | George Hawthorne | 2–8 (2–3) | N/A | |
| 2020 | G. Hawthorne | 2–6 (1–3) | N/A | |
| 2021 | G. Hawthorne | 1-9 (1-4) | N/A | |
| 2022 | Adam Schiermyer | 5-5 (0-5) | N/A | |
| 2023 | A. Schiermyer | 5-5 (2-3) | N/A |