| Official Name: | Skrino |
| Native Name: | Скрино |
| Settlement Type: | Village |
| Pushpin Map: | Bulgaria |
| Pushpin Relief: | 1 |
| Pushpin Label Position: | Location in Bulgaria |
| Subdivision Name: |  Bulgaria |
| Subdivision Type1: | Province |
| Subdivision Name1: | Kyustendil Province |
| Subdivision Type2: | Municipality |
| Subdivision Name2: | Boboshevo |
| Leader Title: | Mayor |
| Area Total Km2: | 15.034 |
| Population As Of: | 2013 |
| Population Total: | 66 |
| Population Footnotes: | [1] |
| Timezone: | EET |
| Utc Offset: | +2 |
| Timezone Dst: | EEST |
| Utc Offset Dst: | +3 |
| Elevation M: | 560 |
| Postal Code Type: | Postal Code |
| Postal Code: | 2663 |
| Coordinates: | 42.1833°N 79°W |
Skrino (Bulgarian: Скрино) is a village in the municipality of Boboshevo, Kyustendil Province, western Bulgaria. As of 2013 it has 66 inhabitants.[1]
The village is located in the Ruen mountain, the northernmost part of the Vlahina mountain range.
Skrino is known under the same name since the 9th century, when it was part of the Bulgarian Empire. It is believed to have been the birthplace of Saint John of Rila, the patron of the Bulgarian people. The Ruen Monastery is situated nearby.
Skrino Rocks in the South Shetland Islands, Antarctica are named after the village.