| Sixte Coupal dit la Reine | |
| Birth Date: | May 1, 1825 |
| Birth Place: | Napierville, Quebec |
| Death Date: | June 22, 1891 |
| Office1: | MP for Napierville Parliament of the Province of Canada 1863-1867 |
| Term Start1: | 1863 |
| Term End1: | July 8, 1872 |
| Predecessor1: | Jacques-Olivier Bureau |
| Successor1: | Antoine-Aimé Dorion |
| Office2: | MP for Napierville |
| Term Start2: | August 4, 1874 |
| Term End2: | May 18, 1882 |
| Predecessor2: | Antoine-Aimé Dorion |
| Successor2: | Médéric Catudal |
| Party: | Liberal |
| Occupation: | Farmer |
Sixte Coupal dit la Reine (May 1, 1825 - June 22, 1891) was a farmer and political figure in Lower Canada and Quebec, Canada. He represented Napierville in the House of Commons of Canada from 1867 to 1872 and from 1874 to 1882 as a Liberal member.
He was born Sixte Coupal in Saint-Cyprien-de-Léry, Lower Canada in 1825. He served as justice of the peace and also as mayor of Napierville. In 1863, he was elected to the Legislative Assembly of the Province of Canada for Napierville as a member of the parti rouge. He was elected again after Confederation but defeated in 1872 and 1874. He was elected in an 1874 by-election but the result was ruled invalid; he was reelected in the by-election that followed.
He died at Saint-Jovite in 1891.