| Sissala East Municipal District | |
| Settlement Type: | Municipal District |
| Pushpin Map: | Ghana |
| Pushpin Map Caption: | Location of Sissala East Municipal District within Upper West |
| Subdivision Type: | Country |
| Subdivision Name: |  Ghana |
| Subdivision Type1: | Region |
| Subdivision Name1: | Upper West |
| Subdivision Type2: | Capital |
| Subdivision Name2: | Tumu |
| Leader Title: | Municipal Chief Executive |
| Leader Name: | Sulemana Alijata Gbentie |
| Population As Of: | 2021 census |
| Population Total: | 80,619[1] |
| Timezone: | GMT |
| Utc Offset: | +0 |
| Coordinates: | 10.8728°N -1.9803°W |
| Iso Code: | GH-UW-SE |
Sissala East Municipal District is one of the eleven districts in Upper West Region, Ghana.[2] [3] Originally it was formerly part of the then-larger Sissala District in 1988; until the western part of the district was later split off to create Sissala West District in July 2004; thus the remaining part has been renamed as Sissala East District, which it was later elevated to municipal district assembly status on 15 March 2018 to become Sissala East Municipal District. The municipality is located in the northeast/eastern part of Upper West Region and has Tumu as its capital town.