| Sisili River | |
| Map: | White Volta Tributaries OSM.png |
| Subdivision Type1: | Country |
| Subdivision Name1: | Ghana |
| Discharge1 Location: | Mouth |
| Source1 Coordinates: | 10.2767°N -1.2417°W |
| Mouth: | Kulpawn River |
The Sisili River is one of the major rivers of northwestern Ghana, along with the Black Volta and Kulpawn Rivers. Historically, the Nakong area of the Sisili River, on the east side, has been subject to "Zabarima slave raids led by Gazare and Babatu".[1]