| Siphesihle Mkhize | |
| Fullname: | Siphesihle Elwin Mkhize[1] |
| Birth Date: | 5 February 1999 |
| Birth Place: | Umlazi, South Africa |
| Height: | 1.80 m |
| Position: | Midfielder |
| Currentclub: | Sekhukhune United |
| Clubnumber: | 15 |
| Youthyears1: | –2019 |
| Youthclubs1: | Mamelodi Sundowns |
| Years1: | 2019–2021 |
| Clubs1: | Mamelodi Sundowns |
| Caps1: | 1 |
| Goals1: | 0 |
| Years2: | 2019–2020 |
| Clubs2: | → Ajax Cape Town (loan) |
| Caps2: | 26 |
| Goals2: | 1 |
| Years3: | 2021–2022 |
| Clubs3: | → Chippa United (loan) |
| Caps3: | 26 |
| Goals3: | 1 |
| Years4: | 2022–2023 |
| Clubs4: | Chippa United |
| Caps4: | 22 |
| Goals4: | 0 |
| Years5: | 2023– |
| Clubs5: | Sekhukhune United |
| Caps5: | 25 |
| Goals5: | 0 |
| Nationalyears1: | 2017–2019 |
| Nationalteam1: | South Africa U20 |
| Nationalcaps1: | 9 |
| Nationalgoals1: | 1 |
| Club-Update: | 15 June 2024 |
| Nationalteam-Update: | 21 July 2020 |
Siphesihle Elwin Mkhize (born 5 February 1999) is a South African soccer player who plays as a midfielder for Sekhukhune United.