| Simone Santi | |
| Birth Date: | 24 May 1966 |
| Birth Place: | Città di Castello, Umbria, Italy |
| Occupation: | Referee |
| Yearsactive: | 1980–present |
Simone Santi (born 24 May 1966) is an Italian volleyball referee. He refereed matches in Europe, Turkey, Bulgary, Russia, Japan, South Korea, Brasil, Argentina. In 2012 he refereed at the London Olympic Games.