| Honorific-Prefix: | Duori Naa |
| Simon Diedong Dombo | |
| Constituency Mp: | Jirapa/Lambussie District |
| Parliament: | Ghana |
| Term Start: | 1969 |
| Term End: | 1972 |
| Office2: | Minister for Interior |
| Term Start2: | 1969 |
| Term End2: | 1971 |
| President2: | Edward Akufo-Addo |
| Primeminister2: | Kofi Abrefa Busia |
| Predecessor2: | John Willie Kofi Harlley |
| Successor2: | Nicholas Yaw Boafo Adade |
| Office3: | Minister for Health |
| President3: | Edward Akufo-Addo |
| Primeminister3: | Kofi Abrefa Busia |
| Predecessor3: | Gibson Dokyi Ampaw |
| Office4: | Duori Naa |
| Term Start4: | 17 April 1949 |
| Term End4: | 19 March 1998 |
| Birth Date: | 1925 |
| Death Date: | 19 March 1998 |
| Nationality: | Ghanaian |
| Party: | Northern People's Party |
| Otherparty: | United Party Progress Party |
Simon Diedong Dombo (1925–1998) was a Ghanaian politician, teacher and chief. He was a Member of Parliament that represented Jirapa-Lambussie District in the first Parliament of the first and second Republic of Ghana.
Simon was born in 1925. He attended Government Teacher Training College Tamale where he obtained his Teachers' Training Certificate.
As the Douri-Na,[1] [2] he was reputed to be the first educated chieftain in the Upper Region of Ghana.[3] He was one of the founders of the Northern People's Party. This later merged with the United Party.
During the Second Republic, he was also a member of the first parliament under the membership of the ruling Progress Party. He was elected in the 1969 Ghanaian general elections.[4] He was Minister for Health and then Minister for Interior[5] in the Busia government.
He was banned from holding elected office by the Supreme Military Council prior to the 1979 elections.[6] S. D. Dombo was among the early educated chieftains.
He was a Catholic Christian and he had more than 30 children.[7] He died on 19 March 1998.