| Sierra de las Ánimas | |
| Country: | Uruguay |
| Geology: | Granite, gneiss |
| Period: | Precambrian |
| Highest: | Cerro de las Ánimas |
| Elevation M: | 501 |
| Coordinates: | -34.8092°N -58.2586°W |
| Range Coordinates: | -34.6°N -72°W |
| Map: | Uruguay |
| Map Size: | 270 |
Sierra de las Ánimas is a hill range which starts in Lavalleja Department of Uruguay and extends south into Maldonado Department.
Here in Maldonado Department it includes one of the highest peaks of Uruguay, the top of Cerro de las Ánimas, near the towns Gregorio Aznárez and Las Flores.
It is the only elevated landform of volcanic origin in Uruguay.
It is a branch of the Cuchilla Grande which extends north - northeast through Treinta y Tres Department into Cerro Largo Department, and which includes secondary ranges.