| Siegmund, Margrave of Brandenburg-Bayreuth | |
| Noble Family: | House of Hohenzollern |
| Father: | Albert III, Margrave of Brandenburg |
| Mother: | Anna of Saxony |
| Birth Date: | 27 September 1468 |
| Birth Place: | Ansbach |
| Death Place: | Ansbach |
Siegmund of Brandenburg-Bayreuth (27 September 1468, in Ansbach – 26 February 1495, in Ansbach) was the sixth, but third surviving, son of Albrecht III, Margrave of Brandenburg, Ansbach and Bayreuth. His mother was his father's second wife, Anna of Saxony. On the death of his father on 11 March 1486, his elder brothers Johann Cicero and Friedrich succeeded to Brandenburg and Ansbach respectively, and Siegmund succeeded to Bayreuth. He never married, and at his death Bayreuth passed to his elder brother Frederick I of Ansbach.