The Men's 25 metre rapid fire pistol singles event of the 2010 Commonwealth Games took place on 8 October 2010, at the CRPF Campus. There was a qualification held to determine the final participants.
| Rank | Name | Country | Stage 1 | Stage 2 | Final | Total | |
|---|---|---|---|---|---|---|---|
| 295 | 288 | 204.5 | 787.5 (FGR) | ||||
| 289 | 287 | 184.3 | 760.3 | ||||
| 289 | 280 | 189.7 | 758.7 | ||||
| 4 | 286 | 278 | 194.2 | 758.2 | |||
| 5 | 280 | 284 | 192.1 | 756.1 | |||
| 6 | 279 | 286 | 190.6 | 755.6 |