| Official Name: | Sheykh Isa |
| Native Name: | شيخ عيسي |
| Settlement Type: | village |
| Pushpin Map: | Iran |
| Mapsize: | 150px |
| Subdivision Type: | Country |
| Subdivision Type1: | Province |
| Subdivision Name1: | Khuzestan |
| Subdivision Type2: | County |
| Subdivision Name2: | Shush |
| Subdivision Type3: | Bakhsh |
| Subdivision Name3: | Central |
| Subdivision Type4: | Rural District |
| Subdivision Name4: | Hoseynabad |
| Population As Of: | 2006 |
| Population Total: | 190 |
| Population Density Km2: | auto |
| Timezone: | IRST |
| Utc Offset: | +3:30 |
| Timezone Dst: | IRDT |
| Utc Offset Dst: | +4:30 |
| Coordinates: | 32.1333°N 48.2736°W |
Sheykh Isa (Persian: شيخ عيسي, also Romanized as Sheykh Īsá; also known as ‘Alam ol Hodá) is a village in Hoseynabad Rural District, in the Central District of Shush County, Khuzestan Province, Iran. At the 2006 census, its population was 190, in 24 families.