| Sheffield-Tuscumbia Twins | |
| Firstseason: | 1926 |
| Lastseason: | 1926 |
| City: | Sheffield, Alabama |
| Past Class Level: | Class D |
| League: | Tri-State League |
The Sheffield-Tuscumbia Twins were a Minor League Baseball team that represented Sheffield, Alabama and Tuscumbia, Alabama in the Tri-State League in 1926.