| Shō Sei Japanese: 尚清 shoo shii | |
| Succession: | King of Ryūkyū |
| Reign: | 1526-1555 |
| Predecessor: | Shō Shin |
| Successor: | Shō Gen |
| Spouse: | Umimajingani Ajiganashi |
| Spouses: | Mazuru-gane, Shirono Ōajishirare Maninaku-gane, Ōajishirare Mayojin-gane, Ōajishirare Yonabaru Agomosirare |
| Spouses-Type: | Concubine |
| Issue: | Shō Tei, Crown Prince Nakagusuku Shō Gen, Prince Kume-Nakagusuku Shō Yōsō, Prince Katsuren Chōsō Shō Kanshin, Prince Ōie Shō Kan, Prince Chatan Chōri Shō Hankoku, Prince Kochinda Chōten Shō Sōken, Prince Ie Chōgi Shō Kōtoku, Prince Yuntanza Chōbyo Shō Kyōrei, Prince Tomigusuku Chōkyō Shō Etsu, Prince Haneji Chōbu Princess Aoriyae Ajiganashi Princess Shuriōkimi Ajiganashi |
| House: | Second Shō dynasty |
| Father: | Shō Shin |
| Mother: | Umitugani Ajiganashi |
| Full Name: | Shō Sei (Japanese: 尚清) |
| Birth Name: | Manikiyotarugani (Japanese: 真仁堯樽金 manichutarugani) |
| Birth Date: | 1497 |
| Death Date: | 1555 |
| Place Of Burial: | Tamaudun, Shuri |
| Native Lang1: | Divine name |
| Native Lang1 Name1: | Tenitsugi-no-ajisohe (Japanese: 天続之按司添 tin chiji nu ajishii)[1] |
was king of the Ryukyu Kingdom from 1526 to 1555.[2] He was the fifth son of King Shō Shin, who he succeeded.
Shō Sei suppressed a rebellion on Amami Ōshima in 1537 and took steps to improve defenses against wakō that same year.
Shō Sei died in 1555 and was succeeded by his second son Shō Gen.