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The Sfântu Gheorghe branch (ro|Brațul Sfântu Gheorghe; uk|Георгіївське гирло) is a distributary of the river Danube, that contributes in forming the Danube Delta.
This is the southernmost branch of the Danube; the other two main branches are the Chilia branch and the Sulina branch. The Sfântu Gheorghe branch runs on a length of, in a southeasterly direction. Its outflow comprises about 22% of the Danube's discharge.