| Setzu | |
| Official Name: | Comune di Setzu |
| Pushpin Map: | Italy Sardinia |
| Coordinates: | 39.7167°N 64°W |
| Region: | Sardinia |
| Province: | South Sardinia |
| Mayor: | Francesco Cotza |
| Area Total Km2: | 7.8 |
| Population Footnotes: | [1] |
| Population Total: | 150 |
| Population As Of: | 30 November 2015 |
| Population Demonym: | Setzesi |
| Elevation M: | 206 |
| Postal Code: | 09029 |
| Area Code: | 070 |
Setzu is a comune (municipality) in the Province of South Sardinia in the Italian region Sardinia, located about 60km (40miles) northwest of Cagliari and about 15km (09miles) north of Sanluri.
Setzu borders the following municipalities: Genoni, Genuri, Gesturi, Tuili, Turri.