| Type: | Bishop |
| Settimio Todisco | |
| Archbishop of the Archdiocese of Brindisi-Ostuni (emeritus) | |
| Church: | Roman Catholic Church |
| See: | Roman Catholic Archdiocese of Brindisi-Ostuni |
| Term: | 1975–2000 |
| Predecessor: | Nicola Margiotta |
| Successor: | Rocco Talucci |
| Ordination: | 27 July 1947 |
| Birth Date: | 10 May 1924 |
| Birth Place: | Brindisi, Italy |
| Previous Post: | Prelate |
Settimio Todisco (born 10 May 1924) is an Italian prelate in the Roman Catholic Church.
Todisco was born in Brindisi and ordained a priest on 27 July 1947. Todisco was appointed Apostolic Administrator of the Diocese of Molfetta-Ruvo-Giovinazzo-Terlizzi, as well as titular bishop of Bigastro, on 15 December 1969 and ordained on 15 February 1970. Todisco was appointed bishop to the Diocese of Brindisi-Ostuni on 24 May 1975 and elevated to archbishop when the diocese changed its name to the Archdiocese of Brindisi-Ostuni in 1986. Todisco retired from archdiocese on 5 February 2000.