| Sessame | |
| Official Name: | Comune di Sessame |
| Coordinates: | 44.6667°N 28°W |
| Region: | Piedmont |
| Province: | Asti (AT) |
| Mayor: | Paolo Carlo Milano |
| Area Total Km2: | 8.45 |
| Population Footnotes: | [1] |
| Population Total: | 251 |
| Population As Of: | 31 December 2019 |
| Population Demonym: | Sessamesi |
| Elevation M: | 325 |
| Postal Code: | 14050 |
| Area Code: | 0144 |
Sessame is a comune (municipality) in the Province of Asti in the Italian region Piedmont, located about 70km (40miles) southeast of Turin and about 30km (20miles) southeast of Asti.
Sessame borders the following municipalities: Bistagno, Cassinasco, Monastero Bormida, Ponti, and Rocchetta Palafea.