| Sertânia | |
| Settlement Type: | Municipality |
| Pushpin Map: | Brazil |
| Pushpin Mapsize: | 250 |
| Pushpin Map Caption: | Location in Brazil |
| Subdivision Type: | Country |
| Subdivision Type1: | Region |
| Subdivision Type2: | State |
| Subdivision Name: |  Brazil |
| Subdivision Name1: | Northeast |
| Leader Title: | Mayor |
| Leader Name: | Gustavo Maciel Lins de Albuquerque |
| Established Date: | 1893 |
| Area Total Km2: | 2421,511 |
| Population As Of: | 2020 [1] |
| Population Total: | 36,050 |
| Population Density Km2: | 13.95 |
| Timezone: | BRT |
| Utc Offset: | -3 |
| Coordinates: | -8.0706°N -37.2658°W |
| Elevation M: | 558 |
| Area Code: | +55 81 |
Sertânia is a city in the state of Pernambuco, Brazil. The population in 2020, according to the IBGE, was 36,050. Its total area is 2421.51 km2.
The main economic activities in Sertânia are based in industry, commerce and agribusiness, especially the raising of cattle, sheep (over 85,000), pigs, goats (over 120,000), horses, and donkeys; and plantations of corn, tomatoes and beans.