| Serodino | |
| Native Name Lang: | es |
| Settlement Type: | Town |
| Pushpin Map: | Argentina |
| Pushpin Map Caption: | Location of Serodino in Argentina |
| Coordinates: | -32.6°N -117°W |
| Subdivision Type: | Country |
| Subdivision Name: | Argentina |
| Subdivision Type1: | Province |
| Subdivision Name1: | Santa Fe |
| Subdivision Type2: | Department |
| Subdivision Name2: | Iriondo |
| Leader Party: | Frente Progresista Cívico y Social |
| Leader Title: | Mayor |
| Leader Name: | Juan Pío Drovetta.[1] |
| Unit Pref: | Metric |
| Area Total Km2: | 149 |
| Population Total: | 3375 |
| Population Density Km2: | auto |
| Timezone1: | ART |
| Utc Offset1: | -3 |
| Postal Code Type: | CPA base |
| Postal Code: | S2216 |
| Area Code Type: | Dialing code |
| Area Code: | +54 3476 |
Serodino is a town (comuna) in the . It is located in the Iriondo Department, 152 km away from the provincial capital (Santa Fe) and 59 km away to Rosario. At the it had a population of 3,375 (2,969 in urban areas).
The economy of the region is based on soybean, corn and wheat produce, and on cattle raising.
The town was founded on December 5, 1885, by Pedro Serodino, who sold the Central Argentino railway company the tract of land where the train station was raised, and built the first house in town (his own).
Serodino is the hometown of Argentine novelist Juan José Saer. On March 19, the festivity of San José is observed.