| Competition: | Serie A |
| Season: | –91 |
| Size: | 280px |
| Dates: | 9 September 1990 – 26 May 1991 |
| Winners: | Sampdoria 1st title |
| Continentalcup1: | European Cup |
| Continentalcup1 Qualifiers: | Sampdoria |
| Continentalcup3: | UEFA Cup |
| Continentalcup3 Qualifiers: | Internazionale Genoa Torino Parma |
| Continentalcup2: | Cup Winners' Cup |
| Continentalcup2 Qualifiers: | Roma |
| Relegated: | Lecce Pisa Cesena Bologna |
| League Topscorer: | Gianluca Vialli (19 goals) |
| Longest Wins: | 20 matches Sampdoria |
| Longest Unbeaten: | 18 matches Sampdoria |
| Longest Winless: | 4 matches Bologna |
| Longest Losses: | 20 matches Pisa |
| Matches: | 306 |
| Total Goals: | 702 |
| Prevseason: | 1989–90 |
| Nextseason: | 1991–92 |
The 1990-91 season saw Sampdoria win the Serie A title for the first time in their history, finishing five points ahead of second placed Milan.[1] Third placed Internazionale were victorious in the UEFA Cup, with ninth-placed Roma compensating for their sub-standard league season with glory in the Coppa Italia, while Juventus's seventh-placed finish meant that they would be without European action for the first season in three decades. Lecce, Pisa, Cesena and Bologna were all relegated.
A notable record was set on 9 December 1990 in a Serie A fixture, when Bologna player Giuseppe Lorenzo was sent off after just 10 seconds for striking an opponent in the match against Parma. This was reportedly the fastest sending off in senior football worldwide at the time.[2]
This is the most recent Serie A season to date in which a team won their first Italian title.
| Team | Head coach | Kit manufacturer | Shirt sponsor | |
|---|---|---|---|---|
| Atalanta |  Bruno Giorgi | Ennerre | Tamoil | |
| Bari | Gaetano Salvemini | Adidas | Sud Factoring | |
| Bologna | Luigi Radice | Uhlsport | Mercatone Uno | |
| Cagliari | Umbro | Formaggi Ovini Sardi | ||
| Cesena | Alberto Batistoni | Adidas | Amadori | |
| Fiorentina |  Sebastião Lazaroni | ABM | La Nazione | |
| Genoa | Osvaldo Bagnoli | Erreà | Mita | |
| Internazionale | Giovanni Trapattoni | Uhlsport | Misura | |
| Juventus | Luigi Maifredi | Kappa | UPIM | |
| Lazio | Dino Zoff | Umbro | Cassa di Risparmio di Roma | |
| Lecce |  Zbigniew Boniek | Adidas | Dreher | |
| Milan | Arrigo Sacchi | Adidas | Mediolanum | |
| Napoli | Alberto Bigon | Ennerre | Mars | |
| Parma | Nevio Scala | Umbro | Parmalat | |
| Pisa | Luca Giannini | Gems | Giocheria | |
| Roma | Ottavio Bianchi | Ennerre | Barilla | |
| Sampdoria | Vujadin Boškov | Asics | Erg | |
| Torino | Emiliano Mondonico | ABM | Indesit |
| Rank | Player | Club | Goals |
|---|---|---|---|
| 1 | Sampdoria | 19 | |
| 2 | Internazionale | 16 | |
| 3 | Genoa | 15 | |
| Genoa | |||
| 5 | Juventus | 14 | |
| Internazionale | |||
| 7 | Giorgio Bresciani | Torino | 13 |
| Massimo Ciocci | Cesena | ||
| Alessandro Melli | Parma | ||
| Bari |