| Competition: | Serie A |
| Winners: | Milan 7th title |
| Season: | 1958–59 |
| Relegated: | Triestina Torino |
| Continentalcup1: | European Cup |
| Continentalcup1 Qualifiers: | Milan |
| League Topscorer: | Antonio Valentín Angelillo (33 goals) |
| Matches: | 306 |
| Total Goals: | 897 |
| Prevseason: | 1957–58 |
| Nextseason: | 1959–60 |
The 1958–59 Serie A season was the 29th edition of Serie A, the top-level football competition in Italy. The championship was won by Milan.
Triestina and Bari had been promoted from Serie B.
| Rank | Player | Club | Goals |
|---|---|---|---|
| 1 |   Antonio Valentín Angelillo | Internazionale | 33 |
| 2 |  José Altafini | Milan | 28 |
| 3 |  Kurt Hamrin | Fiorentina | 26 |
| 4 | Miguel Montuori | Fiorentina | 22 |
| 5 | Eddie Firmani | Internazionale | 20 |
| 6 | John Charles | Juventus | 19 |
| 7 | Sergio Brighenti | Padova | 18 |
| 8 | Ezio Pascutti | Bologna | 17 |
| 9 | Arne Selmosson | Roma | 16 |
| Giancarlo Danova | Milan | ||
| 11 | Dino da Costa | Roma | 15 |
| 12 | Humberto Tozzi | Lazio | 14 |
| Francisco Lojacono | Fiorentina | ||
| Paolo Barison | Genoa | ||
| Omar Sívori | Juventus | ||
| 16 | Bruno Nicolè | Juventus | 13 |
| Aurelio Milani | Sampdoria | ||
| Emanuele Del Vecchio | Napoli |
Source[1]