| Competition: | Serie A |
| Season: | 1940–41 |
| Winners: | Bologna 6th title |
| Relegated: | Novara Bari |
| League Topscorer: | Ettore Puricelli (22 goals) |
| Matches: | 240 |
| Total Goals: | 733 |
| Prevseason: | 1939–40 |
| Nextseason: | 1941–42 |
The 1940–41 Serie A season was won by Bologna.
Atalanta and Livorno had been promoted from Serie B.
| Rank | Player | Club | Goals |
|---|---|---|---|
| 1 |  Ettore Puricelli | Bologna | 22 |
| 2 | Amedeo Amadei | Roma | 18 |
| Romeo Menti | Fiorentina | ||
| 4 | Carlo Reguzzoni | Bologna | 17 |
| 5 | Aldo Boffi | Milano | 16 |
| Guglielmo Gabetto | Juventus | ||
| 7 | Torino | 14 | |
| 8 | Luigi Rosellini | Napoli | 13 |
| 9 | Gino Cappello | Milano | 12 |
| Triestina | |||
| Fiorentina | |||
| 12 |  Michelangelo Pantò | Roma | 11 |
| Genova 1893 | |||
| 14 | Severino Cominelli | Atalanta | 10 |
| Vinicio Viani | Livorno | ||
| Silvio Piola | Lazio |