| Serhiy Matyukhin | |
| Birth Date: | 21 March 1980 |
| Birth Place: | Dachne, Donetsk Oblast, Soviet Union |
| Height: | 1.86 m |
| Position: | Defender |
| Years1: | 1997–2010 |
| Years2: | 1997–2004 |
| Years3: | 2000–2001 |
| Years4: | 2002 |
| Years5: | 2008 |
| Years6: | 2009 |
| Years7: | 2009–2011 |
| Years8: | 2011 |
| Clubs4: | → Kryvbas Kryvyi Rih (loan) |
| Clubs5: | → Kryvbas Kryvyi Rih (loan) |
| Clubs6: | → Arsenal Kyiv (loan) |
| Clubs8: | Oleksandriya |
| Caps1: | 117 |
| Goals1: | 8 |
| Caps2: | 48 |
| Goals2: | 2 |
| Caps3: | 6 |
| Goals3: | 1 |
| Caps4: | 12 |
| Goals4: | 0 |
| Caps5: | 10 |
| Goals5: | 0 |
| Caps6: | 12 |
| Goals6: | 1 |
| Caps7: | 33 |
| Goals7: | 1 |
| Caps8: | 1 |
| Goals8: | 0 |
| Totalcaps: | 239 |
| Totalgoals: | 13 |
| Nationalyears1: | 2004–2005 |
| Nationalteam1: | Ukraine |
| Nationalcaps1: | 3 |
| Nationalgoals1: | 0 |
| Manageryears1: | 2015–2017 |
| Managerclubs1: | Chornomorets Odesa (U-21 assistant) |
Serhiy Matyukhin (Ukrainian: Сергій Матюхін; born 21 March 1980) is a Ukrainian retired professional footballer and coach.
Most of his career, Matyukhin spent in FC Dnipro Dnipropetrovsk from 1997 to 2010. In his early career, he played for FC Dnipro-2 Dnipropetrovsk which is the second team and it used to take part in the professional competitions during that time. In 2009 Matyukhin was loaned to FC Arsenal Kyiv[1] and completed the permanent move in the following league campaign.