| Serhiy Karpenko | |
| Fullname: | Serhiy Vasylyovych Karpenko |
| Birth Date: | 1981 5, df=yes |
| Birth Place: | Boryspil,[1] Ukrainian SSR |
| Position: | Defender |
| Years1: | 1998 |
| Clubs1: | FC Borysfen Boryspil |
| Caps1: | 1 |
| Goals1: | 0 |
| Years2: | 2001–2004 |
| Clubs2: | FC Arsenal Kharkiv |
| Caps2: | 89 |
| Goals2: | 3 |
| Years3: | 2004 |
| Clubs3: | PFC Nyva Vinnytsia |
| Caps3: | 3 |
| Goals3: | 0 |
| Years4: | 2005–2006 |
| Clubs4: | FC Helios Kharkiv |
| Caps4: | 26 |
| Goals4: | 1 |
| Years5: | 2006–2008 |
| Clubs5: | FC Naftovyk-Ukrnafta Okhtyrka |
| Caps5: | 67 |
| Goals5: | 3 |
| Years6: | 2009–2011 |
| Clubs6: | FC Kryvbas Kryvyi Rih |
| Caps6: | 20 |
| Goals6: | 1 |
| Years7: | 2010–2011 |
| Clubs7: | → FC Naftovyk-Ukrnafta Okhtyrka (loan) |
| Caps7: | 34 |
| Goals7: | 3 |
| Years8: | 2012 |
| Clubs8: | FC Lviv |
| Caps8: | 9 |
| Goals8: | 0 |
| Years9: | 2012–2013 |
| Clubs9: | FC Tytan Armyansk |
| Caps9: | 43 |
| Goals9: | 0 |
| Years10: | 2014 |
| Caps10: | 14 |
| Goals10: | 1 |
| Years11: | 2014–2016 |
| Clubs11: | FC Arsenal Kyiv |
| Caps11: | 25 |
| Goals11: | 0 |
| Years12: | 2016 |
| Clubs12: | FC Patriot Baryshivka |
| Caps12: | 12 |
| Goals12: | 0 |
| Years13: | 2017–2018 |
| Clubs13: | FC Avanhard Bziv |
| Manageryears1: | 2017–2019 |
| Managerclubs1: | Avanhard Bziv |
| Manageryears2: | 2020–2021 |
| Managerclubs2: | Polissia Stavky |
| Manageryears3: | 2021–2023 |
| Managerclubs3: | Nyva Buzova |
| Manageryears4: | 2023–2024 |
| Managerclubs4: | Metalist 1925 Kharkiv (U-19) |
| Manageryears5: | 2024– |
| Managerclubs5: | Metalist 1925 Kharkiv (acting) |
Serhiy Karpenko (Ukrainian: Сергій Васильович Карпенко; born 19 May 1981, Boryspil, Kyiv Oblast, Ukrainian SSR) is a former Ukrainian football defender and Ukrainian coach.
Winner of the Persha Liha: 2006–07
Runner-up of the Druha Liha: 2001–02, Group B
Winner of the Ukrainian Amateur Cup: 2018–19
Winner of the Druha Liha: 2022–23