| Sergipe River | |
| Pushpin Map: | Brazil |
| Pushpin Map Caption: | Location of mouth |
| Subdivision Type1: | Country |
| Subdivision Name1: | Brazil |
| Subdivision Type2: | State |
| Subdivision Name2: | Sergipe |
| Source1 Location: | Serra Negra Mountains |
| Source1 Coordinates: | -10.1345°N -37.7729°W |
| Mouth Location: | Aracaju, Barra dos Coqueiros |
| Mouth Coordinates: | -10.9611°N -37.0333°W |
| Basin Size: | 3.673km2 |
| Length: | 210 km |
The Sergipe River (Portuguese: Rio Sergipe) is a river of Sergipe state in northeastern Brazil.