| Sergio Espejo | |
| Birth Date: | 1967 3, df=y |
| Birth Place: | Santiago, Chile |
| Office: | Member of the Chamber of Deputies of Chile |
| Term Start: | 11 March 2014 |
| Term End: | 11 March 2018 |
| Successor: | Dissolution of the District |
| Office1: | Minister of Transport & Telecommunications |
| Term Start1: | 11 March 2006 |
| Term End1: | 27 March 2007 |
| Predecessor1: | Jaime Estévez |
| Successor1: | René Cortázar |
| Party: | Christian Democracy (−2017[1]) |
| Occupation: | Politician |
| Profession: | Lawyer |
| Parents: | Magdalena Yaksic Triantafilo Gilberto Espejo |
| Children: | Five |
Sergio Espejo Yaksic (born 15 March 1967) is a Chilean politician and lawyer.