| Sergio De Gregorio | |
| Birth Date: | 24 February 1946 |
| Birth Place: | Rome, Italy |
| Death Place: | Bremen, Germany |
Sergio De Gregorio (24 February 1946 - 28 January 1966) was an Italian freestyle swimmer. He competed in three events at the 1964 Summer Olympics.[1] He died in the Lufthansa Flight 005 plane crash in Bremen, Germany.[2]