| Serghei Gafina | |
| Birth Date: | 10 November 1984 |
| Birth Place: | Moldova |
| Height: | 1.78 m |
| Currentclub: | Dinamo-Auto Tiraspol |
| Clubnumber: | 30 |
| Position: | Defender |
| Years1: | 2003–2005 |
| Years2: | 2005–2011 |
| Caps2: | 141 |
| Goals2: | 1 |
| Years3: | 2012–2013 |
| Clubs3: | Zimbru Chișinău |
| Caps3: | 13 |
| Goals3: | 0 |
| Years4: | 2014–2020 |
| Clubs4: | Iskra Rîbnița |
| Years5: | 2020– |
| Caps5: | 18 |
| Goals5: | 0 |
| Nationalyears1: | 2010 |
| Nationalteam1: | Moldova |
| Nationalcaps1: | 1 |
| Nationalgoals1: | 0 |
| Pcupdate: | 11:39, 1 June 2021 (UTC) |
Serghei Gafina (born 10 November 1984) is a Moldovan footballer who plays as a defender for Dinamo-Auto Tiraspol in the Moldovan National Division. He has previously played for Iskra-Stal Rîbnița, Zimbru Chișinău and Iskra Rîbnița.