| Sergei Natalushko | |
| Fullname: | Sergei Vladimirovich Natalushko |
| Birth Date: | 13 September 1960 |
| Birth Place: | Zaozyorny, Russian SFSR |
| Position: | Forward |
| Years1: | 1983–1988 |
| Years2: | 1989 |
| Years3: | 1989–1992 |
| Years4: | 1992–1993 |
| Years5: | 1993–1997 |
| Years6: | 1997 |
| Years7: | 1998–2000 |
| Years8: | 2000 |
| Years9: | 2002–2005 |
| Clubs4: | FC Avangard Kamyshin |
| Clubs5: | FC Tekstilshchik Kamyshin |
| Clubs9: | FC Tekstilshchik Kamyshin |
| Caps1: | 10 |
| Caps3: | 120 |
| Caps4: | 19 |
| Caps5: | 120 |
| Caps6: | 7 |
| Caps7: | 49 |
| Caps8: | 13 |
| Caps9: | 28 |
| Goals1: | 3 |
| Goals3: | 24 |
| Goals4: | 5 |
| Goals5: | 27 |
| Goals6: | 2 |
| Goals7: | 16 |
| Goals8: | 2 |
| Goals9: | 2 |
| Manageryears1: | 2004 |
| Managerclubs1: | FC Tekstilshchik Kamyshin (administrator) |
Sergei Vladimirovich Natalushko (Russian: Серге́й Владимирович Наталушко; born 13 September 1960) is a former Russian professional footballer.
He made his professional debut in the Soviet Second League in 1988 for FC Tekstilshchik Kamyshin. He played three games in the UEFA Cup 1994–95 for FC Tekstilshchik Kamyshin.