| Conventional Long Name: | Sanjak of Serfiğe Ottoman Turkish: Liva-i Serfiğe |
| Common Name: | Serfiğe |
| Subdivision: | Sanjak |
| Nation: | the Ottoman Empire |
| Year Start: | 1881 |
| Event End: | First Balkan War |
| Year End: | 1912 |
| Image Map Caption: | Sanjak of Serfiğe, darkest green, late 19th century |
| Capital: | Servia |
| P1: | Sanjak of Tirhala |
| Flag P1: | Flag of the Ottoman Empire.svg |
| P2: | Manastir Vilayet |
| Flag P2: | Flag of the Ottoman Empire.svg |
| S1: | Kingdom of Greece |
| Flag S1: | Flag of Greece (1822-1978).svg |
| Today: | Greece |
The Sanjak of Serfiğe (Greek, Modern (1453-);: Σαντζάκι/Υποδιοίκησις Σερβίων) was a second-level Ottoman province (sanjak or liva) centred on the town of Serfiğe (Servia) in western Macedonia, now part of Greece.
The sanjak was founded in 1881, after the Greek annexation of Thessaly (the sanjak of Tirhala), initially as an independent province, and after 1889 as part of Manastir Vilayet. In 1912, the province encompassed six kazas (districts): Nasliç (Voio), Serfiğe itself, Kozana (Kozani), Kayalar (Ptolemaida), Nasliğ (Neapoli, Kozani), Grebene (Grevena) and Alasonya (Elassona).
The sanjak was conquered by the Greek Army in October 1912, during the First Balkan War.