| Competition: | First League of Serbia and Montenegro |
| Season: | 2005–06 |
| Winners: | Red Star 25th domestic title |
| Relegated: | Javor Rad Obilić |
| Continentalcup1: | Champions League |
| Continentalcup1 Qualifiers: | Red Star |
| Continentalcup2: | UEFA Cup |
| Continentalcup2 Qualifiers: | Partizan Hajduk Kula OFK Beograd |
| Continentalcup3: | Intertoto Cup |
| Continentalcup3 Qualifiers: | Zeta |
| League Topscorer: | Srđan Radonjić (20) |
| Matches: | 240 |
| Total Goals: | 571 |
| Prevseason: | 04-05 |
| Nextseason: | Serbia 06-07 → Montenegro 06-07 |
The 2005–06 Serbia and Montenegro Superliga (officially known as the Meridian SuperLiga for sponsorship reasons) was the fourth and last season of Serbia and Montenegro's top-level football league before the dissolution. It was contested by 16 teams, and won the championship.
Radnički Jugopetrol, Čukarički Stankom and Hajduk Beograd were relegated to the 2005–06 Serbian First League while Sutjeska was relegated to the 2005–06 Montenegrin First League after the last season for finishing last.
The relegated teams were replaced by 2004–05 Serbian First League champions Budućnost Banatski Dvor and runners-up Javor Ivanjica, Rad and Voždovac. The league would also join the 2004–05 Montenegrin First League champion Jedinstvo Bijelo Polje
| Club | City | Stadium | Capacity |
|---|---|---|---|
| Partizan | Belgrade | Partizan Stadium | 32,710 |
| Red Star | Belgrade | Red Star Stadium | 55,538 |
| Vojvodina | Novi Sad | Karađorđe Stadium | 17,204 |
| Zemun | Zemun, Belgrade | Zemun Stadium | 10,000 |
| Hajduk Kula | Kula | Stadion Hajduk | 6,000 |
| Obilić | Belgrade | FK Obilić Stadium | 4,500 |
| Voždovac | Belgrade | Železnik Stadium | 8,000 |
| OFK Beograd | Karaburma, Belgrade | Omladinski Stadium | 20,000 |
| Smederevo | Smederevo | Smederevo City Stadium | 17,200 |
| Zeta | Golubovci | Stadion Trešnjica | 7,000 |
| Borac | Čačak | Čačak Stadium | 6,000 |
| Budućnost Podgorica | Podgorica | Podgorica City Stadium | 17,000 |
| Jedinstvo | Bijelo Polje | Gradski stadion (Bijelo Polje) | 5,000 |
| Javor | Ivanjica | Stadion Ivanjica | 5,000 |
| Budućnost Banatski Dvor | Banatski Dvor | Stadion Mirko Vučurević | 4,000 |
| Rad | Belgrade | Stadion Kralj Petar I | 6,000 |
Champions: RED STAR BELGRADE (coach: 
Walter Zenga)
Players (league matches/league goals)
Takayuki Suzuki (6/0) signed from Kashima Antlers on January 28, 2006 during winter 2005/06 transfer window
Haminu Draman (4/1)