| Serain | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Serain (Aisne).svg |
| Arrondissement: | Saint-Quentin |
| Canton: | Bohain-en-Vermandois |
| Insee: | 02709 |
| Postal Code: | 02110 |
| Mayor: | Claude Ceruso[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Pays du Vermandois |
| Coordinates: | 50.0286°N 3.3667°W |
| Elevation M: | 150 |
| Elevation Min M: | 114 |
| Elevation Max M: | 152 |
| Area Km2: | 6.65 |
Serain (in French pronounced as /səʁɛ̃/) is a commune in the Aisne department in Hauts-de-France in northern France.