| Sergio Melpignano Senior Italian Open | |
| Location: | Fasano, Italy |
| Establishment: | 2004 |
| Course: | San Domenico Golf Club |
| Par: | 72 |
| Yardage: | 6954yd |
| Tour: | European Senior Tour |
| Format: | Stroke play |
| Month Played: | October |
| Aggregate: | 200 James Kingston (2023) |
| To-Par: | −16 as above |
| Current Champion: |  James Kingston |
| Map: | Italy#Italy Apulia |
| Map Label: | San Domenico GC |
| Map Relief: | yes |
| Map Size: | 200 |
| Coordinates: | 40.876°N 17.4°W |
The Senior Italian Open is a men's professional golf tournament for players aged 50 and above which is part of the European Senior Tour schedule. It was played from 2004 to 2008 and then restarted in 2016. The tournament was originally played at GC Venezia, near Venice, but has since been played at GC Arzaga on Lake Garda and GC Udine, Fagagna.
Italy's most successful 20th century male golfer, Costantino Rocca, made his senior debut at the 2007 edition of his home senior open.[1]
| Year | Winner | Score | To par | Margin of victory | Runner(s)-up | Winner's share (€) | Venue | |
|---|---|---|---|---|---|---|---|---|
| Sergio Melpignano Senior Italian Open | ||||||||
| James Kingston (2) | 200 | −16 | 1 stroke | 50,000 | San Domenico | |||
| Italian Senior Open | ||||||||
| 211 | −2 | 3 strokes | 45,000 | Argentario | ||||
| Sergio Melpignano Senior Italian Open | ||||||||
| 205 | −11 | 1 stroke | 44,820 | San Domenico | ||||
| Senior Italian Open | ||||||||
| Cancelled due to the COVID-19 pandemic | ||||||||
| 208 | −8 | Playoff | 45,000 | Villaverde | ||||
 Clark Dennis (2) | 203 | −13 | Playoff | 45,000 | Udine | |||
| 137 | −7 | Playoff | 52,500 | Udine | ||||
| 204 | −9 | 1 stroke | 52,500 | Udine | ||||
| 2009–2015: No tournament | ||||||||
| Lake Garda Italian Seniors Open | ||||||||
| 203 | −13 | 1 stroke | 30,000 | Arzaga | ||||
| Sharp Italian Seniors Open | ||||||||
| 208 | −8 | Playoff | 30,000 | Venezia | ||||
| 205 | −11 | 4 strokes | 26,250 | Venezia | ||||
| Nokia 9300 Italian Seniors Open | ||||||||
| 205 | −11 | Playoff | 25,500 | Venezia | ||||
| Bosch Italian Seniors Open | ||||||||
| 211 | −5 | 1 stroke | 24,000 | Venezia | ||||