| Official Name: | Semyono-Makarensky |
| Native Name: | Семёно-Макаренский |
| Settlement Type: | Khutor |
| Pushpin Map: | Russia Adygea#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Name1: | Adygea |
| Subdivision Name3: | Shovgenovsky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +3:00 |
| Coordinates: | 44.9167°N 54°W[1] |
Semyono-Makarensky (Russian: Семёно-Макаренский) is a rural locality (a khutor) in Dzherokayskoye Rural Settlement of Shovgenovsky District, the Republic of Adygea, Russia. The population was 87 as of 2018.[2] There are four streets.
Semyono-Makarensky is located south of Khakurinokhabl (the district's administrative centre) by road. Volno-Vesyoly is the nearest rural locality.[3]