| Official Name: | Semryukhovo |
| Native Name: | Семрюхово |
| Settlement Type: | Village |
| Pushpin Map: | Russia Vologda Oblast#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Name1: | Vologda Oblast |
| Subdivision Name3: | Vologodsky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +3:00 |
| Coordinates: | 59.5667°N 62°W[1] |
Semryukhovo (Russian: Семрюхово) is a rural locality (a village) in Novlenskoye Rural Settlement, Vologodsky District, Vologda Oblast, Russia. The population was 5 as of 2002.[2]
Semryukhovo is located 53 km northwest of Vologda (the district's administrative centre) by road. Chernevo is the nearest rural locality.[3]