| Semiz Ali | |
| Office1: | 34th Grand Vizier of the Ottoman Empire |
| Term Start1: | 10 July 1561 |
| Term End1: | 28 June 1565 |
| Monarch1: | Suleiman I |
| Predecessor1: | Rüstem Pasha |
| Successor1: | Sokollu Mehmed Pasha |
| Birth Place: | Prača, Ottoman Empire |
| Death Date: | 28 June 1565 |
| Death Place: | Constantinople, Ottoman Empire |
Semiz Ali Pasha (Turkish, Ottoman (1500-1928);: سيمز علي پاشا, Semiz Ali-Paša ) was an Ottoman statesman from the Sanjak of Bosnia who served as Grand Vizier of the Ottoman Empire from 1561 to 1565. He was the beylerbey (governor) of Egypt Eyalet from 1549 to 1553.[1] [2] Semiz Ali Pasha was born in Prača in Bosnia (thus his secondary epithet), and replaced Rüstem Pasha as a Grand Vizier.[3] After palace schooling, he discharged high-level functions along the Ottoman Empire.[3] His epithet "Semiz" means "fat" in Turkish.
In 1561 he negotiated with the ambassador of the Holy Roman Empire, Ogier de Busbecq, on the terms of a peace treaty which was ratified in Vienna in the following year.[4]
In the TV series Muhteşem Yüzyıl, Semiz Ali Pasha was played by the Turkish actor Fatih Dokgöz.