| Honorific-Prefix: | Hon. |
| Seif Ali Iddi | |
| Honorific-Suffix: | MP |
| Office: | Second Vice President of Zanzibar |
| Term Start: | November 2010 |
| Term End: | November 2020 |
| President: | Ali Mohamed Shein |
| Successor: | Hemed Suleiman Abdalla |
| Office2: | Member of Parliament for Kitope |
| Term Start2: | December 2005 |
| Birth Date: | 23 February 1942 |
| Birth Place: | Sultanate of Zanzibar, British protectorate (now in Tanzania) |
| Party: | CCM |
Seif Ali Iddi (born 23 February 1942) is a Tanzanian politician (under CCM political party) and former 2nd Vice President of Zanzibar. He was a Member of Parliament for Kitope constituency from 2000 to 2010.[1]