| Post: | Second Lady or Gentleman |
| Body: | Indonesia |
| Insignia: | National emblem of Indonesia Garuda Pancasila.svg |
| Insigniacaption: | National emblem of Indonesia |
| Incumbent: | Wury Estu Handayani |
| Seat: | Jakarta |
| Abbreviation: | SLOTROI |
| Incumbentsince: | 20 October 2019 |
| Inaugural: | Siti Rahmiati Hatta |
| Termlength: | 5 years |
| Formation: | 18 November 1945 |
Throughout Indonesian history, the title of Second Lady (Indonesian: Ibu Kedua) or, in an instance, Second Gentleman (Indonesian: Tuan Kedua) has been used to refer to the wife or husband of the vice president of Indonesia. While the Constitution of Indonesia does not mention anything about the spouses of the vice president, it continues to hold significant influence in the Indonesian society.
| No | Portrait | Name | Tenure | Age at tenure start | Vice President | Note | |
|---|---|---|---|---|---|---|---|
| 1 | Siti Rahmiati Hatta | 18 November 1945 – 1 December 1956 | Mohammad Hatta 18 November 1945 | [1] | |||
| 2 | KRA Pintakapurnama | 23 March 1973 – 23 March 1978 | Unknown | Hamengkubuwono IX 1940 | [2] | ||
| 3 | Nelly Ilyas Malik | 23 March 1978 – 11 March 1983 | Adam Malik 1942 | [3] | |||
| 4 | Karlinah Djaja Atmadja | 11 March 1983 – 11 March 1988 | Umar Wirahadikusumah 2 February 1957 | [4] | |||
| 5 | Ratu Emma Norma | 11 March 1988 – 11 March 1993 | Sudharmono 1951 | [5] [6] | |||
| 6 | Tuti Sutiawati | 11 March 1993 – 11 March 1998 | Try Sutrisno 5 February 1961 | [7] | |||
| 7 | Hasri Ainun Besari | 11 March 1998 – 21 May 1998 | B. J. Habibie 12 May 1962 | ||||
| 8 | Taufiq Kiemas | 21 October 1999 – 23 July 2001 | Megawati Sukarnoputri 8 March 1973 | ||||
| 9 | Asmaniah | 26 July 2001 – 20 October 2004 | Unknown | Hamzah Haz | |||
| 10 | Mufidah Mi'ad Saad | 20 October 2004 – 20 October 2009 | Jusuf Kalla 27 August 1967 | ||||
| 11 | Herawati | 20 October 2009 – 20 October 2014 | Boediono 16 May 1969 | ||||
| 12 (10) | Mufidah Mi'ad Saad | 20 October 2014 – 20 October 2019 | Jusuf Kalla 27 August 1967 | ||||
| 12 | Wury Estu Handayani | 20 October 2019 – Incumbent | Ma'ruf Amin 31 May 2014 |