Secofentanyl Explained

Secofentanyl is an opioid derivative which is an analogue of fentanyl where the piperidine ring has been cleaved to form an open-chain structure. It is around 40× less potent than fentanyl itself but still 5–6× the potency of morphine in animal tests.^{[1] [2]}

See also

• Benzylfentanyl
• Homofentanyl
• Diampromide
• Fentanyl azepane
• Isofentanyl
• Phenampromide

Notes and References

1. Ivanović MD, Mićović I, Vučković S, Prostran M, Todorović Z, Ivanović E, Kiricojević V, Đorđević JB, Došen-Mićović L . The synthesis and pharmacological evaluation of (+/-)-2, 3-seco-fentanyl analogues. . Journal of the Serbian Chemical Society . 2004 . 69 . 11 . 955–68 . 10.2298/JSC0411955I . free .
2. Lipiński PF, Kosson P, Matalińska J, Roszkowski P, Czarnocki Z, Jarończyk M, Misicka A, Dobrowolski JC, Sadlej J . Fentanyl Family at the Mu-Opioid Receptor: Uniform Assessment of Binding and Computational Analysis . Molecules (Basel, Switzerland) . 24 . 4 . February 2019 . 740 . 30791394 . 6412969 . 10.3390/molecules24040740 . free .