SEC31 explained

SEC31 is a protein which in yeast promotes the formation of COPII transport vesicles from the Endoplasmic Reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.^[1]

Its human homologs are SEC31A and SEC31B.

Further reading

• Tang BL, Zhang T, Low DY, etal . Mammalian homologues of yeast sec31p. An ubiquitously expressed form is localized to endoplasmic reticulum (ER) exit sites and is essential for ER-Golgi transport. . J. Biol. Chem. . 275 . 18 . 13597–604 . 2000 . 10788476 . 10.1074/jbc.275.18.13597. free .
• Stagg SM, Gürkan C, Fowler DM, etal . Structure of the Sec13/31 COPII coat cage. . Nature . 439 . 7073 . 234–8 . 2006 . 16407955 . 10.1038/nature04339. 2006Natur.439..234S . 2426465 .

Notes and References

1. Web site: Entrez Gene: SEC31 SEC31p S. cerevisiae . 2014-09-13 .